Peritonitis is inflammation of the peritoneum. Which symptom cluster is typical?

• A. Nausea, Vomiting, Loss of Appetite, Diarrhea, Fever
• B. Shortness of Breath and Chest Pain
• C. Constipation and Dry Mouth
• D. Rash and Joint Pain

Answer: (D)

Peritonitis presents with irritation of the lining of the abdomen, so you expect symptoms tied to the abdomen plus systemic signs. The most characteristic cluster includes nausea and vomiting, reduced appetite, and fever, often seen with abdominal pain and tender or rigid abdomen. This combination reflects both GI upset and the body’s inflammatory response to peritoneal irritation. Diarrhea can occur in some patients, but fever with nausea/vomiting and anorexia aligns best with this condition.

Shortness of breath and chest pain point more toward heart or lung problems. Constipation and dry mouth could occur with dehydration but don’t capture the abdominal tenderness and inflammatory response central to peritonitis. Rash and joint pain suggest a systemic or autoimmune process rather than a localized abdominal infection.